Figure 4

Knockdown of Rab18 inhibits NSCLC cells growth in vitro. (A,B) qRT-PCR (A) and Western blot analysis (B) were performed to determine the expression level of Rab18 after transfection of Rab18 siRNA and control siRNA in A549 and H23 cells. (C, D) The effects of Rab18 siRNA on A549 (C) and H23 (D) cells proliferation were determined by MTT assay at 24 h, 48 h, and 72 h after transfecting of Rab18 siRNA and control siRNA. (*P < 0.05, **P < 0.01, Student’s t-test).