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Table 2 The inhibitory activity of Jac-A on tumour cells via MTT Assay (IC 50 , μ M, n = 4, mean ± SD)

From: Jacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins

Compound Breast cancer Colon cancer Lung cancer Liver cancer Leukaemia
MBA-MB-231 T47D LOVO A549 HepG2 K562 HL-60 THP-1
Jac-A 22.61 ± 1.2 12.53 ± 1.6 33.24 ± 2.1 18.8 ± 1.6 10.71 ± 1.4 6.52 ± 0.36 9.01 ± 0.47 9.92 ± 0.95
Doxorubicina 0.13 ± 0.01 0.25 ± 0.02 0.24 ± 0.01 0.11 ± 0.01 0.34 ± 0.02 0.55 ± 0.03 0.68 ± 0.02 0.52 ± 0.03
  1. aPositive control.