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Table 1 Binding affinity of Jac-A and (-)-gossypol with Bcl-x L , Bcl-2 or Mcl-1 determined by a fluorescence polarisation assay (Ki, μM)

From: RETRACTED ARTICLE: Jacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins

Compound

Bcl-xL

Bcl-2

Mcl-1

Jac-A

0.46

0.43

1.69

(-)-Gossypol

1.01

0.95

0.86

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BMC Cancer

ISSN: 1471-2407

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