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Table 4 Descriptive characteristics of ovarian cancer cases and controls, the African American Cancer Epidemiology Study (AACES), 2010-14†

From: A multi-center population-based case–control study of ovarian cancer in African-American women: the African American Cancer Epidemiology Study (AACES)

Variable Cases (N = 371) Controls (N = 622)     
  N (%) N (%) OR* (95% CI) OR** (95% CI)
Age group (years)       
20-39 23 (6.2) 77 (12.4)     
40-49 61 (16.4) 115 (18.5)     
50-59 131 (35.3) 219 (35.2)     
60-69 97 (26.1) 157 (25.2)     
70-79 59 (15.9) 54 (8.7)     
Age at menarche (years)       
<12 83 (22.4) 167 (26.8) 1.00 Referent) 1.00 Referent
12-13 186 (50.1) 300 (48.2) 1.22 (0.88-1.69) 1.30 (0.93-1.80)
13+ 102 (27.5) 155 (24.9) 1.27 (0.88-1.84) 1.35 (0.93-1.97)
Parity       
0 67 (18.1) 83 (13.3) 1.00 Referent 1.00 Referent
1-2 159 (42.9) 284 (45.7) 0.66 (0.45-0.97) 0.69 (0.47-1.01)
>3 145 (39.1) 255 (41.0) 0.61 (0.41-0.90) 0.61 (0.41-0.91)
Tubal ligation       
No 235 (63.5) 375 (60.4) 1.00 Referent 1.00 Referent
Yes 135 (36.5) 246 (39.6) 0.84 (0.64-1.10) 0.96 (0.71-1.28)
Missing 1 1     
Oral contraceptive use (months)       
Never to <3 129 (34.8) 145 (23.3) 1.00 Referent 1.00 Referent
3- < 36 102 (27.5) 192 (30.9) 0.64 (0.46-0.91) 0.66 (0.47-0.93)
36 < -60 31 (8.4) 67 (10.8) 0.54 (0.33-0.89) 0.55 (0.33-0.90)
60+ 109 (29.4) 218 (35.0) 0.58 (0.42-0.82) 0.58 (0.41-0.82)
Menopausal status       
Post-menopausal 266 (72.3) 410 (66.2) 1.00 Referent 1.00 Referent
Pre-menopausal 102 (27.7) 209 (33.8) 1.21 (0.78-1.89) 1.23 (0.78-1.92)
Missing 3 3     
Hysterectomy       
No 279 (75.2) 495 (79.6) 1.00 Referent 1.00 Referent
Yes 92 (24.8) 127 (20.4) 1.12 (0.82-1.54) 1.12 (0.82-1.55)
Use of hormone replacement therapy among women over age > =50       
No 216 (75.8) 341 (79.7) 1.00 Referent 1.00 Referent
Yes 69 (24.2) 87 (20.3) 1.17 (0.81-1.69) 1.25 (0.86-1.82)
Missing 2 2     
First degree relative with ovarian cancer       
No 340 (94.7) 578 (96.8) 1.00 Referent 1.00 Referent
Yes 19 (5.3) 19 (3.2) 1.57 (0.82-3.03) 1.60 (0.82-3.12)
Missing 12 25     
First degree relative with breast cancer       
No 281 (77.6) 506 (84.2) 1.00 Referent 1.00 Referent
Yes 81 (22.4) 95 (15.8) 1.46 (1.04-2.04) 1.50 (1.07-2.11)
Missing 9 21     
First degree relative with ovarian and/or breast cancer       
No 267 (73.8) 491 (81.7) 1.00 Referent 1.00 Referent
Yes 95 (26.2) 110 (18.3) 1.50 (1.09-2.06) 1.53 (1.11-2.11)
Missing 9 21     
Body mass index 1 year before diagnosis (kg/m 2 )       
<24.9 54 (14.6) 119 (19.2) 1.00 Referent 1.00 Referent
25–29.9 95 (25.7) 157 (25.3) 1.24 (0.82-1.88) 1.31 (0.86-1.99)
30–34.9 107 (29.0) 157 (25.3) 1.49 (0.99-2.24) 1.50 (0.99-2.27)
> = 35 113 (30.6) 188 (30.3) 1.29 (0.86-1.92) 1.27 (0.85-1.91)
Missing 2 1     
Education       
High school or less 173 (46.6) 223 (35.9) 1.00 Referent 1.00 Referent
Some post-high school training 115 (31.0) 227 (36.6) 0.69 (0.51-0.93) 0.69 (0.51-0.95)
College or graduate degree 83 (22.4) 171 (27.5) 0.66 (0.48-0.93) 0.66 (0.46-0.95)
Missing   1     
Annual Income       
< $10,000 85 (23.4) 130 (21.2) 1.00 Referent 1.00 Referent
$10,000 - < $25,000 98 (26.9) 145 (23.6) 1.00 (0.68-1.46) 1.04 (0.71-1.53)
$25,000 - < $50,000 88 (24.2) 131 (21.3) 1.04 (0.71-1.54) 1.08 (0.72-1.60)
$50,000 - < $75.000 48 (13.2) 103 (16.8) 0.72 (0.46-1.12) 0.75 (0.48-1.19)
≥$75,000 45 (12.4) 105 (17.1) 0.66 (0.42-1.04) 0.73 (0.46-1.17)
Missing 7 8     
Private Physician       
No 104 (29.1) 158 (26.2) 1.00 Referent 1.00 Referent
Yes 253 (70.9) 445 (73.8) 0.77 (0.57-1.03) 0.77 (0.57-1.05)
Missing 14 19     
Current Insurance       
None 41 (11.1) 76 (12.3) 1.00 Referent 1.00 Referent
Medicaid 97 (26.1) 124 (20.0) 1.37 (0.86-2.20) 1.38 (0.85-2.22)
Medicare 96 (25.9) 128 (20.6) 1.04 (0.63-1.74) 1.03 (0.61-1.72)
Other Insurance 137 (36.9) 292 (47.1) 0.84 (0.54-1.29) 0.86 (0.56-1.34)
Missing 0 2     
Ever smoked       
Current/Former 163 (43.9) 259 (41.6) 1.00 Referent 1.00 Referent
Never 208 (56.1) 363 (58.4) 0.97 (0.75-1.27) 1.00 (0.76-1.30)
  1. †Forty-nine patients (32 cases and 17 controls) were excluded from this table due to missing data for either parity or months of oral contraceptive use.
  2. OR = Odds Ratio, CI = Confidence Interval.
  3. *Age adjusted(ORs).
  4. **Multivariable adjusted (ORs) adjusted for age, months of oral contraceptive use, and parity.