Table 2 mtDNA copy number by host characteristics of glioma cases and healthy controls
Variables | Case | Control | Pvalue | ||
|---|---|---|---|---|---|
No. | mtDNA copy number, median (range) | No. | mtDNA copy number, median (range) | ||
Sex | |||||
Male | 241 | 0.98 (0.12 to 3.89) | 241 | 0.70 (0.07 to 2.72) | < 0.001 |
Female | 173 | 1.01 (0.02 to 3.22) | 173 | 0.74 (0.15 to 2.52) | < 0.001 |
P value | 0.431 | 0.101 | |||
Age, years | |||||
<47 | 204 | 0.96 (0.02 to 3.89) | 206 | 0.70 (0.13 to 2.72) | < 0.001 |
≥47 | 210 | 1.03 (0.03 to 3.55) | 208 | 0.72 (0.07 to 2.52) | < 0.001 |
P value | 0.165 | 0.877 | |||
Smoking status | |||||
Never | 318 | 0.98 (0.02 to 3.61) | 329 | 0.69 (0.07 to 2.72) | < 0.001 |
Ever | 96 | 1.02 (0.03 to3.89) | 85 | 0.71 (0.12 to 2.55) | 0.001 |
P value | 0.251 | 0.267 | |||
Family history of cancer | |||||
Yes | 45 | 0.90 (0.03 to 3.26) | 32 | 0.72 (0.18 to 2.66) | 0.002 |
No | 369 | 0.99 (0.02 to 3.89) | 382 | 0.69 (0.07 to 2.72) | < 0.001 |
P value | 0.151 | 0.803 | |||
WHO grade | |||||
I/II | 175 | 0.98 (0.04 to 3.55) | |||
III/IV | 239 | 1.00 (0.02 to 3.89) | |||
P value | 0.982 | ||||