Skip to main content

Table 5 The relationship between clinic-pathological characteristics and cancer specific survival in patients with primary operable invasive ductal breast cancer

From: Immunohistochemical detection improves the prognostic value of lymphatic and blood vessel invasion in primary ductal breast cancer

All patients (n = 360)

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P-value

Hazard ratio (95% CI)

P-value

Age (≤50/ >50 years)

0.97(0.64-1.45)

0.861

  

Size (≤20/ 21-50/ >50 mm)

2.16(1.52-3.05)

<0.001

1.58(1.09-2.29)

0.014

Grade (I / II / III)

1.84(1.31-2.57)

<0.001

1.43(1.00-2.05)

0.049

Involved lymph node (-ve/+ve)

2.83(1.87-4.28)

<0.001

1.82(1.17-2.83)

0.008

ER (no/yes)

0.59(0.39-0.89)

0.012

 

0.571

PR (no/yes)

0.72(0.48-1.09)

0.128

  

HER2 status (no/yes)

1.34(0.84-2.14)

0.216

  

Endocrine therapy (no/yes)

0.48(0.26-0.88)

0.018

 

0.114

Chemotherapy (no/yes)

1.56(1.05-2.33)

0.029

 

0.611

LBVIH&E (absent/present)

2.39(1.61-3.54)

<0.001

 

0.196

LVID2–40 (absent/present)

3.31(2.19-4.97)

<0.001

1.69(1.08-2.67)

0.023

BVIFVIII (absent/present)

5.12(3.38-7.78)

<0.001

3.35(2.21-5.63)

<0.001

Node-negative patients (n = 212)

    

age (≤50/ >50 years)

0.69(0.36-1.36)

0.290

  

Size (≤20/ 21-50/ >50 mm)

2.33(2.32-3.31)

0.007

1.93(1.04-3.59)

0.038

Grade (I / II / III)

1.64(1.64-2.74)

0.061

 

0.184

ER (no/yes)

0.75(0.38-1.45)

0.388

  

PR (no/yes)

0.91(0.47-1.78)

0.780

  

HER2 status (no/yes)

2.11(1.03-4.31)

0.040

 

0.368

Endocrine therapy (no/yes)

0.91(0.41-2.02)

0.822

  

Chemotherapy (no/yes)

0.83(0.39-1.72)

0.612

  

LBVIH&E (absent/present)

2.43(1.21-4.89)

0.010

 

0.649

LVID2–40 (absent/present)

3.24(1.67-6.29)

0.001

2.29(1.15-4.58)

0.004

BVIFVIII (absent/present)

6.03(2.87-13.77)

<0.001

4.43(2.07-9.51)

0.001

Triple-negative patients (n = 120)

    

age (<50/ >50 years)

1.09(0.57-2.01)

0.784

  

Size (≤20/ 21-50/ >50 mm)

3.43(2.01-5.85)

<0.001

2.94(1.65-5.24)

<0.001

Grade (I / II / III)

0.79(0.39-1.58)

0.503

  

Involved lymph node (-ve/+ve)

4.08(2.01-8.27)

<0.001

2.36(1.11-5.03)

0.026

Endocrine therapy (no/yes)

0.89(0.27-2.89)

0.842

  

Chemotherapy (no/yes)

0.93(0.48-1.78)

0.824

  

LBVIH&E (absent/present)

2.31(1.21-4.42)

0.011

 

0.294

LVID2–40 (absent/present)

3.57(1.82-7.04)

<0.001

2.61(1.36-5.04)

0.014

BVIFVIII (absent/present)

4.68(3.09-10.31)

<0.001

3.63(1.38-6.56)

0.001