Intervention group (n = 30) | Control group (n = 30) | p-value | |||
---|---|---|---|---|---|
n | % | n | % | ||
Age (years) | |||||
Mean (SD) | 61.3 (10.1) | 64.1 (10.9) | 0.304 | ||
Gender | |||||
Male | 14 | 46.7 | 19 | 63.3 | 0.195 |
Female | 16 | 53.3 | 11 | 36.7 | |
Weight (kg, SD) | 74.3 (14.7) | 72.7 (12.1) | 0.553 | ||
Height (cm, SD) | 171.2 (8.3) | 172.3 (7.5) | 0.906 | ||
Body mass index | |||||
Mean (SD) | 25.3 (4.5) | 24.4 (3.6) | 0.559 | ||
Karnofsky-index (median, range) | 80 (70–100) | 80 (70–100) | 1.000 | ||
Primary site | |||||
Lung cancer | 12 | 9.2 | 8 | 26.6 | 0.320 |
Breast cancer | 5 | 16.7 | 6 | 20.1 | 0.542 |
Prostate cancer | 5 | 16.7 | 9 | 30.1 | 0.156 |
Melanoma | 1 | 3.3 | 1 | 3.3 | 1.000 |
Renal cancer | 1 | 3.3 | 2 | 6.7 | 0.875 |
Other | 6 | 20.1 | 4 | 13.4 | 0.325 |
Localization metastases | 0.717 | ||||
Thoracic | 17 | 56.7 | 14 | 46.7 | |
Lumbar | 9 | 30.0 | 13 | 43.3 | |
Thoracic and lumbar | 2 | 6.7 | 2 | 6.7 | |
Sacrum | 2 | 6.7 | 1 | 3.3 | |
Number metastases | 0.257 | ||||
Mean (range) | 1.4 (2–4) | 1.7 (1–5) | |||
Solitary | 22 | 73.3 | 18 | 60.0 | |
Multiple | 8 | 26.7 | 12 | 40.0 | |
Type of metastases | 0.961 | ||||
Mixed | 2 | 6.7 | 2 | 6.7 | 1.000 |
Osteoblast | 9 | 30.0 | 10 | 33.3 | 0.956 |
Osteolytic | 19 | 63.3 | 18 | 60.0 | .0932 |
Distant metastases at baseline | |||||
Visceral | 12 | 40.0 | 5 | 16.7 | 0.045 |
Brain | 3 | 10.0 | 3 | 10.0 | 1.000 |
Lung | 7 | 23.3 | 4 | 13.3 | 0.320 |
Tissue | 8 | 26.7 | 6 | 20.0 | 0.542 |
Hormonotherapy | 10 | 33.3 | 16 | 53.3 | 0.118 |
Immunotherapy | 7 | 23.3 | 5 | 16.7 | 0.519 |
Chemotherapy | 25 | 83.3 | 20 | 66.7 | 0.136 |
Pathological fracture at baseline | 6 | 20.0 | 9 | 30.0 | 0.379 |
Neurological deficit | 0 | 0.0 | 2 | 6.7 | 0.150 |
Orthopedic corset at baseline | 7 | 23.3 | 5 | 16.7 | 0.519 |
Radiotherapy dose completed (Gy) | 0.136 | ||||
Single dose (median, range) | 3 (2–4) | 3 (2–4) | 1.000 | ||
Cumulative dose (median, range) | 30 (30–40) | 30 (30–40) | 1.000 |