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Table 4 Two way contingency table analysis showing predictive accuracy of the nomogram

From: Postoperative nomogram to predict the probability of metastasis in Enneking stage IIB extremity osteosarcoma

  Training set Validation set
  Observed (N) Observed (N)
  Metastasis positive Metastasis free Total Metastasis positive Metastasis free Total
Expected (N) Metastasis positive 28 13 41 14 2 16
  Metastasis free 6 44 50 4 14 18
  Total 34 57 91 18 16 34
Accuracy % (95% CI) 79.1 (0.69 to 0.86) 82.4 (0.63 to 0.92)
Sensitivity % (95% CI) 82.4 (0.69 to 0.92) 77.8 (0.60 to 0.87)
Specificity % (95% CI) 77.2 (0.69 to 0.83) 87.5 (0.67 to 0.98)
PPV % (95% CI) 68.3 (0.57 to 0.76) 87.5 (0.67 to 0.98)
NPV % (95% CI) 88.0 (0.79 to 0.95) 77.8 (0.60 to 0.87)
PLR (95% CI) 3.61 (2.21 to 5.36) 6.22 (1.83 to 35.63)
NLR (95% CI) 0.23 (0.10 to 0.456) 0.25 (0.14 to 0.60)
DOR (95% CI) 15.80 (4.84 to 54.44) 24.5 (3.07 to 261.90)
  1. Abbreviations: CI confidential interval, PPV positive predictive value, NPV negative predictive value, PLR positive likelihood ratio, NLR negative likelihood ratio, DOR diagnostic odds ratio.