Variables | Training (N= 91) | Validation (N= 34) | |||
---|---|---|---|---|---|
Ā | N | % | N | % | |
Survival | 5 years survivor (CDF from definitive surgery) | 58 | 63.7 | 16 | 47.1 |
Ā | 5 years survivor (NED after metastasectomy) | 6 | 6.6 | 2 | 5.9 |
Ā | DOD | 27 | 29.7 | 7 | 20.6 |
Ā | NED (after metastasectomy) < 5 years | 0 | 0.0 | 6 | 17.6 |
Ā | AWD | 0 | 0.0 | 2 | 5.9 |
Ā | DOC | 0 | 0.0 | 1 | 2.9 |
Metastasis | Positive | 34 | 37.4 | 17 | 50.0 |
Ā | Free | 57 | 62.6 | 17 | 50.0 |
Sex | Male | 50 | 54.9 | 19 | 55.9 |
Ā | Female | 41 | 45.1 | 15 | 44.1 |
Age | ā¤ 14 yrs | 36 | 39.6 | 17 | 50.0 |
Ā | > 15 yrs | 55 | 60.4 | 17 | 50.0 |
Tumor site | Distal femur | 46 | 50.5 | 12 | 35.3 |
Ā | Proximal tibia | 17 | 18.7 | 7 | 20.6 |
Ā | Proximal humerus | 14 | 15.4 | 5 | 14.7 |
Ā | Others | 14 | 15.4 | 10 | 29.4 |
Tumor size | ā„ 8cm | 62 | 68.1 | 20 | 58.8 |
Ā | < 8cm | 29 | 31.9 | 14 | 41.2 |
Pathologic fx at diagnosis | Yes | 5 | 5.5 | 2 | 5.9 |
Ā | No | 86 | 94.5 | 32 | 94.1 |
Skip lesion | Yes | 3 | 3.3 | 2 | 5.9 |
Ā | No | 88 | 96.7 | 32 | 94.1 |
Intracapsular extension | Yes | 20 | 22.0 | 10 | 29.4 |
Ā | No | 71 | 78.0 | 24 | 70.6 |
ALP | Elevation | 56 | 61.5 | 11 | 32.4 |
Ā | Normal | 35 | 38.5 | 23 | 67.6 |
LDH | Elevation | 9 | 9.9 | 5 | 14.7 |
Ā | Normal | 53 | 58.2 | 16 | 47.1 |
Ā | NA | 29 | 31.9 | 13 | 38.2 |
Histologic type | Osteoblastic | 62 | 68.1 | 17 | 50.0 |
Ā | Chondroblastic | 11 | 12.1 | 3 | 8.8 |
Ā | Fibroblastic | 4 | 4.4 | 1 | 2.9 |
Ā | Mixed | 12 | 13.2 | 5 | 14.7 |
Ā | Others | 2 | 2.2 | 3 | 8.8 |
Ā | NA | 0 | 0.0 | 5 | 14.7 |
Huvos grade | III and IV | 65 | 71.4 | 21 | 61.8 |
Ā | I and II | 26 | 28.6 | 13 | 38.2 |
Operation Type | Limb salvage surgery | 91 | 100.0 | 23 | 67.6 |
Ā | Amputation | 0 | 0.0 | 11 | 32.4 |
Surgeon factor | Surgeon 1 | 91 | 100.0 | 22 | 64.7 |
Ā | Surgeon 2 | 0 | 0.0 | 10 | 29.4 |
Ā | Surgeon 3 | 0 | 0.0 | 2 | 5.9 |
Surgical resection | R0 | 85 | 93.4 | 33 | 97.1 |
Ā | R1 | 6 | 6.6 | 1 | 2.9 |