Explicative variables | Relative risk (95% CI) | p-value |
---|
EBV-T
+
| 2.36.104 (152.9-3.7 106) | <0.0001 |
Grade
| 11.52 (2.28-58.28) | 0.003 |
EBV-P
+
| 122 (1.5-9.8 103) | 0.03 |
Lymph node invasion
| 16.59 (2.5-110) | 0.004 |
EBV-T
+
: grade
| 0.0082 (0.00071-0.0094) | 0.0001 |
EBV-P
+
: HER-2
| 254 (7.88–8.19 103) | 0.002 |
EBV-P
+
: grade
| 0.16 (0.03-0.96) | 0.045 |
- EBV: Epstein-Barr virus; T+: detected in tumors; P+: detected in PBMCs; HER-2: human epidermal growth factor receptor 2.
- The hazard function for the model with EBV variables reads as:
.
- The relative risk (RR) >1 corresponds to a negative effect, i.e. a decrease in patient survival, while an RR <1 corresponds to a positive effect, i.e. an increase in patient survival. “95% CI” stands for the confidence interval at 95%. The variable “Grade” includes all grades.