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Table 1 Parameters of the univariate analysis of clinicopathological factors

From: Epstein-Barr virus infection and clinical outcome in breast cancer patients correlate with immune cell TNF-α/IFN-γ response

Explicative variables Relative risk (95% CI) p-value
Tumor size 2.04 (1.412–2.95) 0.00015
Grade 1 - -
Grade 2 1.38 (0.30–6.30) 0.679
Grade 3 2.92 (0.63–13.54) 0.171
Relapse 14.95 (5.67–39.44) <0.0001
EBV-T + 0.795 (0.291–2.173) 0.65
EBV-P + 1.05 (0.44–2.51) 0.91
ER/PR positive 0.48 (0.19–1.20) 0.116
HER-2 positive 2.71 (0.795–9.21) 0.111
Lymph node invasion 6.32 (2.31–17.3) 0.0003
Anti-ZEBRA antibody titration 4,63 (1.75–12.23) 0.002
  1. EBV: Epstein-Barr virus; T+: detected in tumors; P+: detected in PBMCs; ER/PR: estrogen/progesterone receptor; HER-2: human epidermal growth factor receptor 2; anti-ZEBRA: antibodies to BamH1 Z Epstein-Barr replication activator.