Prognostic value of
in ER-negative breast cancers. For the public breast cancer microarray data, we pooled all eligible breast cancers after normalizing. We performed Kaplan-Meier analysis of RRM2 for the OS (A) and PFS (B) of breast cancer patients. Cox proportional analysis results are shown for OS and PFS in (C) and (D). Findings were verified in the ZJU set. The prognostic performance of RRM2 for ER-negative and ER-positive breast cancers is shown in (E) and (F), respectively.