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Table 2 Univariate analysis of the prognostic factors for patients with gastric cancer in overall and early stage

From: Histopathology-based prognostic score is independent prognostic factor of gastric carcinoma

Variables Overall Early stage
  Cases n(%) 5-year OS(%) P value Cases n(%) 5-year OS(%) P value
Gender 932    0.311 90   82.2 0.07
  Male 669 71.8 37.8   65 72.2 86.2  
  Female 263 28.2 43.1   25 27.8 72.0  
Age(years)     0.062     0.32
  ≤65 533 57.2 34.3   66 73.3 83.3  
  >65 399 42.8 43.0   24 26.7 79.2  
Size     <0.001     0.714
  ≤4 cm 224 24.0 59.2   57 63.3 82.5  
  >4 cm 708 76.0 33.0   33 36.7 81.8  
Location     <0.001     0.149
  Lower 672 72.1 42.1   75 83.3 85.3  
  Middle 99 10.6 37.6   9 10.0 66.7  
  Upper 115 12.3 36.5   6 6.7 66.7  
  Entire 46 4.9 25.4   0 0.0 0.0  
Macroscopic Type     <0.001     
  Early stage 90 10.7 81.0      
  Borrmann I 30 2.1 42.1      
  Borrmann II 145 15.6 40.7      
  Borrmann III 614 65.9 34.2      
  Borrmann IV 52 5.6 13.7      
Lauren grade     0.003     0.218
  Intestinal 455 48.8 50.4   38 42.2 86.5  
  Diffuse 477 51.2 37.1   52 57.8 73.1  
Histologic type     0.334     0.263
  Mixed-type 272 29.2 40.3   37 41.1 61.3  
  Well-differentiated 61 6.5 57.9   7 7.8 83.7  
  Medium-differentiated 112 12.0 43.7   8 8.9 53.9  
  Poorly-differentiated 365 39.2 37.5   34 37.8 40.2  
  Mucinous 58 6.2 38.6   1 1.1 100.0  
  Signet-ring cell 29 3.1 47.8   3 3.3 33.3  
  Undifferentiated 30 3.2 21.4   0 0.0 0.0  
  Squamous cell 5 0.5 25.0   0 0.0 0.0  
Histologic type 2     0.504     0.958
  Differentiated 380 40.8 37.6   59 65.6 83.1  
  Undifferentiated 552 59.2 40.5   31 34.4 80.6  
Histologic type 3     0.032     0.016
  Singal-type 684 73.3 39.3   56 62.2 89.1  
  Mixed-type 246 26.4 39.3   34 37.8 72.4  
Histologic Grading     <0.001     <0.001
  1 63 6.8 82.5   30 30.0 93.3  
  2 352 37.7 62.0   45 50.0 88.6  
  3 399 42.8 26.2   17 18.9 78.6  
  4 118 12.6 6.8   1 1.1 0.0  
T Stage     <0.001     
  T1 90 9.7 82.2      
  T2 185 19.8 50.8      
  T3 418 44.8 36.5      
  T4 239 25.6 19.0      
N Stage     <0.001     0.06
  N0 288 30.9 63.8   65 72.2 86.2  
  N1 168 18.0 43.7   13 14.4 76.9  
  N2 189 20.3 34.0   10 11.1 70.0  
  N3 287 22.5 12.2   2 2.2 50.0  
Lymphovascular invasion     0.032     
  Negative 208 22.3 40.7      
  Positive 724 77.7 22.6      
Peritoneal metastasis     0.022     
  Absent 889 88.9 39.8      
  Present 43 11.1 19.5      
Hepatic metastasis     0.014     
  Absent 878 90.3 38.7      
  Present 54 9.6 16.8