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Table 2 Patients characteristics according to the presence of malignant tumors

From: Characterization of the rs2802292 SNP identifies FOXO3Aas a modifier locus predicting cancer risk in patients with PJS and PHTS hamartomatous polyposis syndromes

  

Malignant tumors

 

Variable

Category

No

Yes

p-value

n

 

106

26

 

Age

 

31.00 (3.00-78.00)

48.00 (13.00-85.00)

0.001

Age at diagnosis

 

17.00 (1.00-72.00)

24.50 (5.00-77.00)

0.0421

Genotype

GG

28 (26.42)

5 (19.23)

0.1062

 

TG

48 (45.28)

8 (30.77)

 
 

TT

30 (28.30)

13 (50.00)

 

Genotype (2 levels)

XG

76 (71.70)

13 (50.00)

0.0344

 

TT

30 (28.30)

13 (50.00)

 

Mutation

LKB1

56 (52.83)

16 (61.54)

0.4242

 

PTEN

50 (47.17)

10 (38.46)

 

Sex

F

39 (36.79)

17 (65.38)

0.0082

 

M

67 (63.21)

9 (34.62)

 

Benign tumors

No

27 (25.47)

3 (11.54)

0.1287

 

Yes

79 (74.53)

23 (88.46)

 

G.I. benign tumors

No

43 (40.57)

4 (15.38)

0.0163

 

Yes

63 (59.43)

22 (84.62)

 

G.I. malignant tumors

No

106 (100.00)

21 (80.77)

<0.0001

 

Yes

0 (0.00)

5 (19.23)

 
  1. Data are expressed as medians and interquartile range, and frequency and percentages, for continuous and categorical variables, respectively. P values refer to Pearson’s χ2 and Mann–Whitney U tests for categorical and continuous variables, respectively.