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Table 2 Patients characteristics according to the presence of malignant tumors

From: Characterization of the rs2802292 SNP identifies FOXO3Aas a modifier locus predicting cancer risk in patients with PJS and PHTS hamartomatous polyposis syndromes

   Malignant tumors  
Variable Category No Yes p-value
n   106 26  
Age   31.00 (3.00-78.00) 48.00 (13.00-85.00) 0.001
Age at diagnosis   17.00 (1.00-72.00) 24.50 (5.00-77.00) 0.0421
Genotype GG 28 (26.42) 5 (19.23) 0.1062
  TG 48 (45.28) 8 (30.77)  
  TT 30 (28.30) 13 (50.00)  
Genotype (2 levels) XG 76 (71.70) 13 (50.00) 0.0344
  TT 30 (28.30) 13 (50.00)  
Mutation LKB1 56 (52.83) 16 (61.54) 0.4242
  PTEN 50 (47.17) 10 (38.46)  
Sex F 39 (36.79) 17 (65.38) 0.0082
  M 67 (63.21) 9 (34.62)  
Benign tumors No 27 (25.47) 3 (11.54) 0.1287
  Yes 79 (74.53) 23 (88.46)  
G.I. benign tumors No 43 (40.57) 4 (15.38) 0.0163
  Yes 63 (59.43) 22 (84.62)  
G.I. malignant tumors No 106 (100.00) 21 (80.77) <0.0001
  Yes 0 (0.00) 5 (19.23)  
  1. Data are expressed as medians and interquartile range, and frequency and percentages, for continuous and categorical variables, respectively. P values refer to Pearson’s χ2 and Mann–Whitney U tests for categorical and continuous variables, respectively.