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Figure 2 | BMC Cancer

Figure 2

From: Characterization of the rs2802292 SNP identifies FOXO3Aas a modifier locus predicting cancer risk in patients with PJS and PHTS hamartomatous polyposis syndromes

Figure 2

GG genotype is associated with increased expression of FoxO3A both at the mRNA and protein level. HT-29, LS174T, HCT-116 and Caco-2 human intestinal cells were typed for the rs2802292 polymorphism and then analyzed by quantitative real-time PCR (A) and immunoblotting (B) to measure FoxO3A mRNA and protein expression. β-Actin was used as a loading control.

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