Skip to main content

Table 2 Cox proportional hazards multivariate regression model parameters

From: Prognostic model for predicting overall survival in children and adolescents with rhabdomyosarcoma

Covariate

Beta coefficient

Hazard ratio

95% CI

p

Age

-0.037*

-**

-

0.154

Age’

0.089*

-**

-

0.013

Size

0.006

-††

-

0.095

Size’

-0.004

-††

-

0.359

Favorable site

-0.204

0.82

0.65-1.02

0.076

Stage

    

Regional

0.404

1.50

1.13-1.98

0.004

Distant

1.259

3.52

2.64-4.70

<0.001

Histology

    

Alveolar

0.497

1.64

1.35-2.00

<0.001

Other

-0.135

0.87

0.59-1.29

0.499

Received surgery

-0.612

0.54

0.40-0.72

<0.001

Received RT

-0.632

0.53

0.42-0.68

<0.001

Interaction terms

    

Surgery × RT

0.564

1.75

1.24-2.50

0.002

  1. CI, confidence interval; RT, radiotherapy.
  2. *Age was modeled using a restricted cubic spline function with three knots, which yields two independent beta coefficients, annotated as Age and Age’.
  3. **The hazard ratio varies continuously with age.
  4. Size was modeled using a restricted cubic spline function with three knots, which yields two independent beta coefficients, annotated as Size and Size’.
  5. ††The hazard ratio varies continuously with size.