Variable | Cutoff level | Number | Survival rates (%) | Univariate | Multivariate | ||
---|---|---|---|---|---|---|---|
1 year | 3 year | p-value | RR (95% CI) | P | |||
Age (year) | 0.980 | ||||||
< 60 | 26 | 42.1 | 8.0 | ||||
≥ 60 | 221 | 25.5 | 15.3 | ||||
Sex | 0.477 | ||||||
Male | 21 | 36.6 | 24.4 | ||||
Female | 26 | 39.6 | 29.7 | ||||
Preoperative biliary drainage | 0.968 | ||||||
Present | 19 | 37.9 | 6.3 | ||||
Absent | 28 | 38.5 | 8.7 | ||||
Associated gallstone | 0.341 | ||||||
Present | 26 | 53.8 | 11.5 | ||||
Absent | 21 | 54.5 | 0.0 | ||||
Curability | 0.004 | 2.845 (1.314–6.158) | 0.008 | ||||
Curative | 36 | 47.0 | 7.2 | ||||
Non-curative | 11 | 9.1 | 0.0 | ||||
Tumor location | 0.699 | ||||||
Gallbladder neck | 28 | 42.5 | 8.5 | ||||
Gallbladder body/fundus | 19 | 30.7 | 0.0 | ||||
pT (TNM) | 0.170 | ||||||
pT1 and 2 | 16 | 42.2 | 12.7 | ||||
pT3 and 4 | 31 | 35.2 | 4.4 | ||||
Lymph node metastasis | 0.328 | ||||||
Negative | 17 | 47.1 | 7.8 | ||||
Positive | 30 | 32.2 | 10.1 | ||||
Histologic differentiation | 0.432 | ||||||
Well/Moderate | 43 | 38.8 | 6.0 | ||||
Poor | 4 | 25.0 | 0.0 | ||||
Hepatic invasion | 0.728 | ||||||
Present | 26 | 30.5 | 6.1 | ||||
Absent | 21 | 46.2 | 8.8 | ||||
CRAO | 0.728 | ||||||
Present | 11 | 43.6 | 0.0 | ||||
Absent | 36 | 35.9 | 7.2 | ||||
Intraoperative blood infusion | 0.893 | ||||||
Present | 25 | 34.5 | 12.9 | ||||
Absent | 22 | 41.5 | 0.0 | ||||
Adjuvant therapy | 0.179 | ||||||
Yes | 7 | 51.4 | 25.7 | ||||
No | 40 | 35.6 | 4.9 | ||||
Overall | 47 | 37.8 | 6.0 |