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Table 6 Univariate and multivariate analyses of 14 variables related to survival of GBC patients with preoperative jaundice (n = 47)

From: The prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer

Variable Cutoff level Number Survival rates (%) Univariate Multivariate
  1 year 3 year p-value RR (95% CI) P
Age (year) 0.980   
  < 60 26 42.1 8.0    
  ≥ 60 221 25.5 15.3    
Sex 0.477   
  Male 21 36.6 24.4    
  Female 26 39.6 29.7    
Preoperative biliary drainage 0.968   
  Present 19 37.9 6.3    
  Absent 28 38.5 8.7    
Associated gallstone 0.341   
  Present 26 53.8 11.5    
  Absent 21 54.5 0.0    
Curability      0.004 2.845 (1.314–6.158) 0.008
  Curative 36 47.0 7.2    
  Non-curative 11 9.1 0.0    
Tumor location 0.699   
Gallbladder neck 28 42.5 8.5    
Gallbladder body/fundus 19 30.7 0.0    
pT (TNM)      0.170   
  pT1 and 2 16 42.2 12.7    
  pT3 and 4 31 35.2 4.4    
Lymph node metastasis 0.328   
  Negative 17 47.1 7.8    
  Positive 30 32.2 10.1    
Histologic differentiation 0.432   
Well/Moderate 43 38.8 6.0    
  Poor 4 25.0 0.0    
Hepatic invasion 0.728   
  Present 26 30.5 6.1    
  Absent 21 46.2 8.8    
CRAO      0.728   
  Present 11 43.6 0.0    
  Absent 36 35.9 7.2    
Intraoperative blood infusion 0.893   
  Present 25 34.5 12.9    
  Absent 22 41.5 0.0    
Adjuvant therapy 0.179   
  Yes 7 51.4 25.7    
  No 40 35.6 4.9    
  Overall 47 37.8 6.0