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Table 6 Univariate and multivariate analyses of 14 variables related to survival of GBC patients with preoperative jaundice (n = 47)

From: The prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer

Variable

Cutoff level

Number

Survival rates (%)

Univariate

Multivariate

 

1 year

3 year

p-value

RR (95% CI)

P

Age (year)

0.980

  
 

< 60

26

42.1

8.0

   
 

≥ 60

221

25.5

15.3

   

Sex

0.477

  
 

Male

21

36.6

24.4

   
 

Female

26

39.6

29.7

   

Preoperative biliary drainage

0.968

  
 

Present

19

37.9

6.3

   
 

Absent

28

38.5

8.7

   

Associated gallstone

0.341

  
 

Present

26

53.8

11.5

   
 

Absent

21

54.5

0.0

   

Curability

    

0.004

2.845 (1.314–6.158)

0.008

 

Curative

36

47.0

7.2

   
 

Non-curative

11

9.1

0.0

   

Tumor location

0.699

  

Gallbladder neck

28

42.5

8.5

   

Gallbladder body/fundus

19

30.7

0.0

   

pT (TNM)

    

0.170

  
 

pT1 and 2

16

42.2

12.7

   
 

pT3 and 4

31

35.2

4.4

   

Lymph node metastasis

0.328

  
 

Negative

17

47.1

7.8

   
 

Positive

30

32.2

10.1

   

Histologic differentiation

0.432

  

Well/Moderate

43

38.8

6.0

   
 

Poor

4

25.0

0.0

   

Hepatic invasion

0.728

  
 

Present

26

30.5

6.1

   
 

Absent

21

46.2

8.8

   

CRAO

    

0.728

  
 

Present

11

43.6

0.0

   
 

Absent

36

35.9

7.2

   

Intraoperative blood infusion

0.893

  
 

Present

25

34.5

12.9

   
 

Absent

22

41.5

0.0

   

Adjuvant therapy

0.179

  
 

Yes

7

51.4

25.7

   
 

No

40

35.6

4.9

   
 

Overall

47

37.8

6.0

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