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Table 6 Univariate and multivariate analyses of 14 variables related to survival of GBC patients with preoperative jaundice (n = 47)
| Variable | Cutoff level | Number | Survival rates (%) | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|---|
| 1 year | 3 year | p-value | RR (95% CI) | P | |||
| Age (year) | 0.980 | ||||||
| < 60 | 26 | 42.1 | 8.0 | ||||
| ≥ 60 | 221 | 25.5 | 15.3 | ||||
| Sex | 0.477 | ||||||
| Male | 21 | 36.6 | 24.4 | ||||
| Female | 26 | 39.6 | 29.7 | ||||
| Preoperative biliary drainage | 0.968 | ||||||
| Present | 19 | 37.9 | 6.3 | ||||
| Absent | 28 | 38.5 | 8.7 | ||||
| Associated gallstone | 0.341 | ||||||
| Present | 26 | 53.8 | 11.5 | ||||
| Absent | 21 | 54.5 | 0.0 | ||||
| Curability | 0.004 | 2.845 (1.314–6.158) | 0.008 | ||||
| Curative | 36 | 47.0 | 7.2 | ||||
| Non-curative | 11 | 9.1 | 0.0 | ||||
| Tumor location | 0.699 | ||||||
| Gallbladder neck | 28 | 42.5 | 8.5 | ||||
| Gallbladder body/fundus | 19 | 30.7 | 0.0 | ||||
| pT (TNM) | 0.170 | ||||||
| pT1 and 2 | 16 | 42.2 | 12.7 | ||||
| pT3 and 4 | 31 | 35.2 | 4.4 | ||||
| Lymph node metastasis | 0.328 | ||||||
| Negative | 17 | 47.1 | 7.8 | ||||
| Positive | 30 | 32.2 | 10.1 | ||||
| Histologic differentiation | 0.432 | ||||||
| Well/Moderate | 43 | 38.8 | 6.0 | ||||
| Poor | 4 | 25.0 | 0.0 | ||||
| Hepatic invasion | 0.728 | ||||||
| Present | 26 | 30.5 | 6.1 | ||||
| Absent | 21 | 46.2 | 8.8 | ||||
| CRAO | 0.728 | ||||||
| Present | 11 | 43.6 | 0.0 | ||||
| Absent | 36 | 35.9 | 7.2 | ||||
| Intraoperative blood infusion | 0.893 | ||||||
| Present | 25 | 34.5 | 12.9 | ||||
| Absent | 22 | 41.5 | 0.0 | ||||
| Adjuvant therapy | 0.179 | ||||||
| Yes | 7 | 51.4 | 25.7 | ||||
| No | 40 | 35.6 | 4.9 | ||||
| Overall | 47 | 37.8 | 6.0 | ||||
