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Table 4 Univariate analysis of 14 variables related to survival of GBC patients who underwent surgical resection with curative intent (n = 192)
| Variable | Cutoff level | Number | Survival rates (%) | p-value | |
|---|---|---|---|---|---|
| 3 year | 5 year | ||||
| Age (year) | 0.012 | ||||
| < 60 | 107 | 43.2 | 39.0 | ||
| ≥ 60 | 85 | 25.5 | 15.3 | ||
| Sex | 0.805 | ||||
| Male | 66 | 34.9 | 24.4 | ||
| Female | 126 | 35.9 | 29.7 | ||
| Jaundice | < 0.001 | ||||
| Present | 47 | 6.0 | 6.0 | ||
| Absent | 145 | 42.9 | 36.0 | ||
| Associated gallstone | 0.577 | ||||
| Present | 106 | 35.3 | 25.8 | ||
| Absent | 86 | 35.3 | 30.9 | ||
| Curability | < 0.001 | ||||
| Curative | 163 | 40.4 | 32.1 | ||
| Non-curative | 29 | 7.9 | 7.9 | ||
| Tumor location | < 0.001 | ||||
| Gallbladder neck | 54 | 12.7 | 9.5 | ||
| Gallbladder body/fundus | 138 | 44.0 | 35.9 | ||
| pT (TNM) | < 0.001 | ||||
| pT1 and 2 | 95 | 57.4 | 49.5 | ||
| pT3 and 4 | 97 | 12.8 | 6.4 | ||
| Lymph node metastasis | < 0.001 | ||||
| Negative | 90 | 55.1 | 43.5 | ||
| Positive | 102 | 17.5 | 14.6 | ||
| Histologic differentiation | 0.154 | ||||
| Well/Moderate | 161 | 36.0 | 30.8 | ||
| Poor | 31 | 32.1 | 11.5 | ||
| Hepatic invasion | < 0.001 | ||||
| Present | 90 | 14.2 | 6.7 | ||
| Absent | 102 | 53.1 | 45.9 | ||
| CRAO | < 0.001 | ||||
| Present | 15 | 0.0 | 0.0 | ||
| Absent | 177 | 36.0 | 28.7 | ||
| Combined portal vein/hepatic artery resection | 0.041 | ||||
| Present | 5 | 0.0 | 0.0 | ||
| Absent | 187 | 37.8 | 30.1 | ||
| Intraoperative blood infusion | 0.011 | ||||
| Present | 44 | 16.6 | 5.5 | ||
| Absent | 148 | 41.1 | 35.2 | ||
| Adjuvant therapy | 0.782 | ||||
| Yes | 28 | 31.6 | 13.2 | ||
| No | 164 | 35.8 | 30.4 | ||
| Overall | 192 | 35.3 | 28.1 | ||
