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Table 1 Demographic data of jaundiced (n = 47) and non-jaundiced GBC patients (n = 145)

From: The prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer

 

Jaundiced, n

Non-jaundiced, n

p-value

Male gender

21

45

0.088

Mean age (range)

57.5 ± 11.0(35-80)

58.2 ± 10.2(23-83)

0.725

Postoperative hospital stay

19.7 ± 13.3 (4–85)

11.5 ± 6.4 (5–51)

< 0.001

Associated gallbladder disease

0.983

 Gallstones

26 (55.3%)

80 (55.2%)

 

 Gallbladder polyp

1 (2.1%)

3 (2.0%)

 

Nil

20 (42.6%)

62 (42.8%)

 

Tumor location

  

< 0.001

Gallbladder neck

28 (59.6)

26 (17.9)

 

Gallbladder body

10 (21.3)

70 (48.3)

 

Gallbladder fundus

9 (19.1)

49 (33.8)

 

Histologic type

0.259

 Well differentiated

2 (4.3)

9 (6.2)

 

 Moderately differentiated

41 (87.2)

109 (75.2)

 

Poorly differentiated

4 (8.5)

27 (18.6)

 

Extent of liver resection

0.590

 Major hepatectomy (>3 segments)

4

4

 

 Anatomical segments IV-V

8

42

 

Gallbladder bed

35

99

 

Extrahepatic bile duct resection

44 (93.6)

12 (8.3%)

< 0.001

Pathologic extrahepatic bile duct invasion

38 (80.9)

12 (8.3%)

< 0.001

Combined resection of adjacent organs

11 (23.4%)

4 (2.8%)

< 0.001

Hepatic invasion

26 (55.3%)

64 (44.1%)

0.183

Lymph node metastasis

30 (63.8%)

72 (49.7%)

0.091

Vascular invasion

2 (4.3)

3 (2.1%)

0.415

pT

0.019

 pT1-2

16 (34.1%)

78 (53.8%)

 

 pT3-4

31 (65.9%)

67 (46.2%)

 

Intra-operative bleeding (mL)

754.3 ± 600.9 (200–3200)

386.0 ± 251.8(200–1800)

0.001

Operative time (min)

310.0 ± 82.7 (100–470)

224.3 ± 77.3(100–400)

< 0.001

R0

36 (76.6%)

127 (87.6%)

0.068

Mortality (number of patients)

3 (6.4%)

3 (2.1%)

0.141

Morbidity (need invasive treatment)

16 (34.0%)

18 (12.4%)

0.001

  1. Note that adjacent organs include the pancreas, duodenum, stomach, and/or colon other than the liver and extrahepatic bile duct.