Skip to main content

Advertisement

Table 1 Demographic data of jaundiced (n = 47) and non-jaundiced GBC patients (n = 145)

From: The prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer

  Jaundiced, n Non-jaundiced, n p-value
Male gender 21 45 0.088
Mean age (range) 57.5 ± 11.0(35-80) 58.2 ± 10.2(23-83) 0.725
Postoperative hospital stay 19.7 ± 13.3 (4–85) 11.5 ± 6.4 (5–51) < 0.001
Associated gallbladder disease 0.983
 Gallstones 26 (55.3%) 80 (55.2%)  
 Gallbladder polyp 1 (2.1%) 3 (2.0%)  
Nil 20 (42.6%) 62 (42.8%)  
Tumor location    < 0.001
Gallbladder neck 28 (59.6) 26 (17.9)  
Gallbladder body 10 (21.3) 70 (48.3)  
Gallbladder fundus 9 (19.1) 49 (33.8)  
Histologic type 0.259
 Well differentiated 2 (4.3) 9 (6.2)  
 Moderately differentiated 41 (87.2) 109 (75.2)  
Poorly differentiated 4 (8.5) 27 (18.6)  
Extent of liver resection 0.590
 Major hepatectomy (>3 segments) 4 4  
 Anatomical segments IV-V 8 42  
Gallbladder bed 35 99  
Extrahepatic bile duct resection 44 (93.6) 12 (8.3%) < 0.001
Pathologic extrahepatic bile duct invasion 38 (80.9) 12 (8.3%) < 0.001
Combined resection of adjacent organs 11 (23.4%) 4 (2.8%) < 0.001
Hepatic invasion 26 (55.3%) 64 (44.1%) 0.183
Lymph node metastasis 30 (63.8%) 72 (49.7%) 0.091
Vascular invasion 2 (4.3) 3 (2.1%) 0.415
pT 0.019
 pT1-2 16 (34.1%) 78 (53.8%)  
 pT3-4 31 (65.9%) 67 (46.2%)  
Intra-operative bleeding (mL) 754.3 ± 600.9 (200–3200) 386.0 ± 251.8(200–1800) 0.001
Operative time (min) 310.0 ± 82.7 (100–470) 224.3 ± 77.3(100–400) < 0.001
R0 36 (76.6%) 127 (87.6%) 0.068
Mortality (number of patients) 3 (6.4%) 3 (2.1%) 0.141
Morbidity (need invasive treatment) 16 (34.0%) 18 (12.4%) 0.001
  1. Note that adjacent organs include the pancreas, duodenum, stomach, and/or colon other than the liver and extrahepatic bile duct.