Skip to main content

Table 3 Uni- and multivariate Cox regression analyses for clinical characteristics and DKK-1 serum levels on overall survival in patients with prostate cancer

From: High serum levels of Dickkopf-1 are associated with a poor prognosis in prostate cancer patients

Variables Univariate analyses Multivariate analyses
  HR 95% CI P value HR 95% CI P value
Age (years) 1.04 0.96-1.13 0.34 not included   
pT (pT3/4 vs. pT2) 11.30 2.64-48.45 0.001 8.76 1.85-41.47 0.006
pN (pN1 vs. pN0) 2.89 1.19-7.01 0.02    n.s.
Gleason 7.22 2.51-20.75 <0.001 3.34 1.10-10.29 0.036
PSA (ng/ml) 0.99 0.96-1.04 0.93 not included   
DKK-1 (high vs. low) 3.01 1.18-7.63 0.02 3.73 1.44-9.66 0.007
  1. Abbreviations: CI = confidence interval; HR = hazard ratio.