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Table 1 Analysis of the gene expression data using the DAVID functional annotation tool

From: Erythropoietin suppresses the activation of pro-apoptotic genes in head and neck squamous cell carcinoma xenografts exposed to surgical trauma

 

24 h

48 h

24 and 48 h

Biological theme (pathway)

Genes (No)

P-value

Genes (No)

P-value

Genes (No)

P-value

Apoptosis

81

6.0 × 10-4

97

3.0 × 10-2

20

1.5 × 10-4

Programmed cell death

82

6.0 × 10-4

99

6.0 × 10-4

19

3.7 × 10-4

VEGF-signalling

8

5.5 × 10-1

12

2.5 × 10-1

0

n.a.

Angiogenesis

9

9.7 × 10-1

0

n.a.

0

n.a.

Blood vessel development

20

8.3 × 10-1

0

n.a.

0

n.a.

Response to hypoxia

0

n.a.

0

n.a.

0

n.a.

  1. NOTE The table shows the number of genes with significantly altered expression involved in pathways related to angiogenesis, hypoxia and apoptosis. The p-value was defined as the EASE score which is a more stringent form of Fishers exact p-value.