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Table 3 List of downregulated microRNA in ALDH positive MECs derived from normal parous as compared to virgin mammary gland of rat

From: microRNA alterations in ALDH positive mammary epithelial cells: a crucial contributing factor towards breast cancer risk reduction in case of early pregnancy

miRNA

PREDICTED TARGET GENES (from gene array)

DOWNREGUALTED

UPREGULATED

rno-miR-143

LIFR

rno-let-7a, 7d, 7e, 7b, 7c, 7f, 7i

ACVR1C, PPARGC1A

rno-miR-26a, 26b

ACVR1C

rno-miR-30a, 30e, 30c, 30d

LIFR, PPARGC1A, PPARGC1B

rno-miR-181a, 181b

ACVR1C, RGMA

rno-miR-140

LIFR

rno-miR-322

RGMA

rno-miR-27b

ACVR1C, ISL1, PPARG, LIFR, SMAD9

rno-miR-23ab

ACVR1C, Isl1, PPARG

rno-miR-93

RGMA, NEUROG2, PPARGC1B

rno-miR-425

ACVR1C

rno-miR-15b

RGMA

rno-miR-25

PPARGC1B

rno-miR-125a-5p

ACVR1C, LIFR

rno-miR-195

RGMA

rno-miR-128 ab

ACVR1C, ISL1, PPARG, LIFR, SMAD9

rno-miR-342-3p

LIFR

rno-miR-29 ac

ISL1, NOTCH2

rno-miR-140-3p

ACVR1C, PPARGC1A

rno-miR-103

PPARGC1A,CCNE1

rno-miR-423

PPARGC1B, TCF7L2