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Table 3 Joint effect of unfavorable SNP genotypes associated with hepatocellular carcinoma risk

From: High-resolution melting analysis reveals genetic polymorphisms in MicroRNAs confer hepatocellular carcinoma risk in Chinese patients

No. of unfavorable SNPsa

Controls n (%)

HCCs n (%)

AORb(95% CI)

P

0

82 (20.2)

39(12.4)

1.00

 

1

261 (64.1)

177 (56.4)

1.40 (0.91-2.14)

0.126

2

64 (15.7)

98 (31.2)

3.11 (1.89-5.09)

7.18x10−6

  1. AOR, adjusted odds ratio; CI, confidence interval.
  2. aUnfavorable genotypes were potentially risk genotypes (CT + CC for miR-196a2 and miR-499).
  3. bORs were adjusted for age and sex.