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Table 5 The association of time between diagnosis and first major resection with excess mortality, stratified by subsite and stage

From: The association of time between diagnosis and major resection with poorer colorectal cancer survival: a retrospective cohort study

Variable/Model

Time between diagnosis and major resection

Less than 25 days

25-38 days

More than 38 days

 

Excess hazards ratio

95% Confidence interval

Excess hazards ratio

Excess hazards ratio

95% Confidence interval

Subsite

         

Colon

         

  Crude model

1.92

1.68

to

2.19

1.00

1.18

1.01

to

1.40

  Age-adjusted

1.91

1.68

to

2.17

1.00

1.17

1.00

to

1.37

  Adjusted for all covariates1

1.71

1.50

to

1.94

1.00

1.19

1.02

to

1.38

Rectosigmoid

         

  Crude model

1.59

1.14

to

2.22

1.00

1.12

0.78

to

1.61

  Age-adjusted

1.54

1.12

to

2.12

1.00

1.02

0.72

to

1.46

  Adjusted for all covariates1

1.31

0.96

to

1.79

1.00

1.03

0.74

to

1.45

Rectum

         

  Crude model

1.28

1.05

to

1.55

1.00

1.11

0.93

to

1.34

  Age-adjusted

1.28

1.07

to

1.54

1.00

1.09

0.91

to

1.30

  Adjusted for all covariates1

1.17

0.97

to

1.39

1.00

1.11

0.94

to

1.32

Stage

         

A

         

  Crude model

1.56

1.13

to

2.15

1.00

1.25

0.91

to

1.72

  Age-adjusted

1.66

1.22

to

2.25

1.00

1.29

0.95

to

1.74

  Adjusted for all covariates2

1.58

1.16

to

2.14

1.00

1.25

0.93

to

1.68

B

         

  Crude model

1.60

1.44

to

1.78

1.00

1.22

1.08

to

1.38

  Age-adjusted

1.58

1.43

to

1.75

1.00

1.19

1.05

to

1.33

  Adjusted for all covariates2

1.52

1.37

to

1.68

1.00

1.15

1.02

to

1.29

  1. 1adjusted for age, sex, region of residence, stage, grade, morphology, deprivation quintile and period.
  2. 2adjusted for age, sex, region of residence, subsite, grade, morphology, deprivation quintile and period.