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Figure 3 | BMC Cancer

Figure 3

From: c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells

Figure 3

NOX-4 knockdown reduced α-SMA expression in response to TGF-β stimulus. A. RMF-EG cells were infected with viral particles (prepared as described in Material and Methods) carrying a sequence specific shRNA targeting NOX4 or a non-related sequence. After an infection period of 48 h, in the presence or absence of 5 ng/ml of TGF-β1 proteins were analyzed by western blot to a-SMA and NOX4. B. Columns represents mean ± SE of α-SMA signal to Actin from densitometric analysis of three independent experiments.

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