TY - JOUR AU - Mueller, M. M. AU - Fusenig, N. E. PY - 2004 DA - 2004// TI - Friends or foes - bipolar effects of the tumour stroma in cancer JO - Nat Rev Cancer VL - 4 UR - https://doi.org/10.1038/nrc1477 DO - 10.1038/nrc1477 ID - Mueller2004 ER - TY - JOUR AU - Ronnov-Jessen, L. AU - Bissell, M. J. PY - 2009 DA - 2009// TI - Breast cancer by proxy: can the microenvironment be both the cause and consequence? JO - Trends Mol Med VL - 15 UR - https://doi.org/10.1016/j.molmed.2008.11.001 DO - 10.1016/j.molmed.2008.11.001 ID - Ronnov-Jessen2009 ER - TY - JOUR AU - Egeblad, M. AU - Littlepage, L. E. AU - Werb, Z. PY - 2005 DA - 2005// TI - The fibroblastic coconspirator in cancer progression JO - Cold Spring Harb Symp Quant Biol VL - 70 UR - https://doi.org/10.1101/sqb.2005.70.007 DO - 10.1101/sqb.2005.70.007 ID - Egeblad2005 ER - TY - JOUR AU - Beacham, D. A. AU - Cukierman, E. PY - 2005 DA - 2005// TI - Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression JO - Semin Cancer Biol VL - 15 UR - https://doi.org/10.1016/j.semcancer.2005.05.003 DO - 10.1016/j.semcancer.2005.05.003 ID - Beacham2005 ER - TY - JOUR AU - Elenbaas, B. AU - Weinberg, R. A. PY - 2001 DA - 2001// TI - Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation JO - Exp Cell Res VL - 264 UR - https://doi.org/10.1006/excr.2000.5133 DO - 10.1006/excr.2000.5133 ID - Elenbaas2001 ER - TY - JOUR AU - Bissell, M. J. AU - Radisky, D. C. AU - Rizki, A. AU - Weaver, V. M. AU - Petersen, O. W. PY - 2002 DA - 2002// TI - The organizing principle: microenvironmental influences in the normal and malignant breast JO - Differentiation VL - 70 UR - https://doi.org/10.1046/j.1432-0436.2002.700907.x DO - 10.1046/j.1432-0436.2002.700907.x ID - Bissell2002 ER - TY - JOUR AU - Kuperwasser, C. AU - Chavarria, T. AU - Wu, M. AU - Magrane, G. AU - Gray, J. W. AU - Carey, L. AU - Richardson, A. AU - Weinberg, R. A. PY - 2004 DA - 2004// TI - Reconstruction of functionally normal and malignant human breast tissues in mice JO - Proc Natl Acad Sci U S A VL - 101 UR - https://doi.org/10.1073/pnas.0401064101 DO - 10.1073/pnas.0401064101 ID - Kuperwasser2004 ER - TY - JOUR AU - Fiaschi, T. AU - Chiarugi, P. PY - 2012 DA - 2012// TI - Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison JO - Int J Cell Biol VL - 2012 UR - https://doi.org/10.1155/2012/762825 DO - 10.1155/2012/762825 ID - Fiaschi2012 ER - TY - JOUR AU - Storz, P. PY - 2005 DA - 2005// TI - Reactive oxygen species in tumor progression JO - Front Biosci VL - 10 UR - https://doi.org/10.2741/1667 DO - 10.2741/1667 ID - Storz2005 ER - TY - JOUR AU - Dröge, W. PY - 2002 DA - 2002// TI - Free radicals in the physiological control of cell function JO - Physiol Rev VL - 82 UR - https://doi.org/10.1152/physrev.00018.2001 DO - 10.1152/physrev.00018.2001 ID - Dröge2002 ER - TY - JOUR AU - Tobar, N. AU - Guerrero, J. AU - Smith, P. C. AU - Martinez, J. PY - 2010 DA - 2010// TI - NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration JO - Br J Cancer VL - 103 UR - https://doi.org/10.1038/sj.bjc.6605847 DO - 10.1038/sj.bjc.6605847 ID - Tobar2010 ER - TY - JOUR AU - De Wever, O. AU - Demetter, P. AU - Mareel, M. AU - Bracke, M. PY - 2008 DA - 2008// TI - Stromal myofibroblasts are drivers of invasive cancer growth JO - Int J Cancer VL - 123 UR - https://doi.org/10.1002/ijc.23925 DO - 10.1002/ijc.23925 ID - De Wever2008 ER - TY - JOUR AU - Radisky, D. C. AU - Przybylo, J. A. PY - 2008 DA - 2008// TI - Matrix Metalloproteinase–induced Fibrosis and Malignancy in Breast and Lung JO - Proc Am Thorac Soc VL - 5 UR - https://doi.org/10.1513/pats.200711-166DR DO - 10.1513/pats.200711-166DR ID - Radisky2008 ER - TY - JOUR AU - Shimoda, M. AU - Mellody, K. T. AU - Orimo, A. PY - 2010 DA - 2010// TI - Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression JO - Semin Cell Dev Biol VL - 21 UR - https://doi.org/10.1016/j.semcdb.2009.10.002 DO - 10.1016/j.semcdb.2009.10.002 ID - Shimoda2010 ER - TY - JOUR AU - Tomasek, J. J. AU - Gabbiani, G. AU - Hinz, B. AU - Chaponnier, C. AU - Brown, R. A. PY - 2002 DA - 2002// TI - Myofibroblasts and mechano-regulation of connective tissue remodelling JO - Nat Rev Mol Cell Biol VL - 3 UR - https://doi.org/10.1038/nrm809 DO - 10.1038/nrm809 ID - Tomasek2002 ER - TY - JOUR AU - Moustakas, A. AU - Heldin, C. -. H. PY - 2005 DA - 2005// TI - Non-Smad TGF-β signals JO - J Cell Sci VL - 118 UR - https://doi.org/10.1242/jcs.02554 DO - 10.1242/jcs.02554 ID - Moustakas2005 ER - TY - JOUR AU - Samarakoon, R. AU - Overstreet, J. M. AU - Higgins, P. J. PY - 2013 DA - 2013// TI - TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities JO - Cell Signal VL - 25 UR - https://doi.org/10.1016/j.cellsig.2012.10.003 DO - 10.1016/j.cellsig.2012.10.003 ID - Samarakoon2013 ER - TY - JOUR AU - Wrana, J. L. AU - Attisano, L. AU - Cárcamo, J. AU - Zentella, A. AU - Doody, J. AU - Laiho, M. AU - Wang, X. -. F. AU - Massague, J. PY - 1992 DA - 1992// TI - TGFβ signals through a heteromeric protein kinase receptor complex JO - Cell VL - 71 UR - https://doi.org/10.1016/0092-8674(92)90395-S DO - 10.1016/0092-8674(92)90395-S ID - Wrana1992 ER - TY - JOUR AU - Benhar, M. AU - Dalyot, I. AU - Engelberg, D. AU - Levitzki, A. PY - 2001 DA - 2001// TI - Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress JO - Mol Cell Biol VL - 21 UR - https://doi.org/10.1128/MCB.21.20.6913-6926.2001 DO - 10.1128/MCB.21.20.6913-6926.2001 ID - Benhar2001 ER - TY - JOUR AU - Arancibia, R. AU - Caceres, M. AU - Martinez, J. AU - Smith, P. C. PY - 2009 DA - 2009// TI - Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts JO - J Periodontal Res VL - 44 UR - https://doi.org/10.1111/j.1600-0765.2008.01184.x DO - 10.1111/j.1600-0765.2008.01184.x ID - Arancibia2009 ER - TY - JOUR AU - Ushio-Fukai, M. AU - Nakamura, Y. PY - 2008 DA - 2008// TI - Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy JO - Cancer Lett VL - 266 UR - https://doi.org/10.1016/j.canlet.2008.02.044 DO - 10.1016/j.canlet.2008.02.044 ID - Ushio-Fukai2008 ER - TY - JOUR AU - Engel, M. E. AU - McDonnell, M. A. AU - Law, B. K. AU - Moses, H. L. PY - 1999 DA - 1999// TI - Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.52.37413 DO - 10.1074/jbc.274.52.37413 ID - Engel1999 ER - TY - JOUR AU - Curtin, J. F. AU - Cotter, T. G. PY - 2004 DA - 2004// TI - JNK Regulates HIPK3 Expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells JO - 17100 VL - 279 ID - Curtin2004 ER - TY - JOUR AU - Hasebe, T. AU - Tsuda, H. AU - Hirohashi, S. AU - Shimosato, Y. AU - Tsubono, Y. AU - Yamamoto, H. AU - Mukai, K. PY - 1998 DA - 1998// TI - Fibrotic focus in infiltrating ductal carcinoma of the breast: a significant histopathological prognostic parameter for predicting the long-term survival of the patients JO - Breast Cancer Res Treat VL - 49 UR - https://doi.org/10.1023/A:1006067513634 DO - 10.1023/A:1006067513634 ID - Hasebe1998 ER - TY - JOUR AU - Sampson, N. AU - Koziel, R. AU - Zenzmaier, C. AU - Bubendorf, L. AU - Plas, E. AU - Jansen-Dürr, P. AU - Berger, P. PY - 2011 DA - 2011// TI - ROS Signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma JO - Mol Endocrinol VL - 25 UR - https://doi.org/10.1210/me.2010-0340 DO - 10.1210/me.2010-0340 ID - Sampson2011 ER - TY - JOUR AU - Cucoranu, I. AU - Clempus, R. AU - Dikalova, A. AU - Phelan, P. J. AU - Ariyan, S. AU - Dikalov, S. AU - Sorescu, D. PY - 2005 DA - 2005// TI - NAD(P)H oxidase 4 mediates transforming growth factor-β1–induced differentiation of cardiac fibroblasts into myofibroblasts JO - Circ Res VL - 97 UR - https://doi.org/10.1161/01.RES.0000187457.24338.3D DO - 10.1161/01.RES.0000187457.24338.3D ID - Cucoranu2005 ER - TY - JOUR AU - Jain, M. AU - Rivera, S. AU - Monclus, E. A. AU - Synenki, L. AU - Zirk, A. AU - Eisenbart, J. AU - Feghali-Bostwick, C. AU - Mutlu, G. M. AU - Budinger, G. R. AU - Chandel, N. S. PY - 2013 DA - 2013// TI - Mitochondrial reactive oxygen species regulate transforming growth factor-beta signaling JO - J Biol Chem VL - 288 UR - https://doi.org/10.1074/jbc.M112.431973 DO - 10.1074/jbc.M112.431973 ID - Jain2013 ER - TY - JOUR AU - Li, Y. AU - Trush, M. A. PY - 1998 DA - 1998// TI - Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production JO - Biochem Biophys Res Commun VL - 253 UR - https://doi.org/10.1006/bbrc.1998.9729 DO - 10.1006/bbrc.1998.9729 ID - Li1998 ER - TY - JOUR AU - Liu, R. M. AU - Choi, J. AU - Wu, J. H. AU - Gaston Pravia, K. A. AU - Lewis, K. M. AU - Brand, J. D. AU - Mochel, N. S. AU - Krzywanski, D. M. AU - Lambeth, J. D. AU - Hagood, J. S. AU - Forman, H. J. AU - Thannickal, V. J. AU - Postlethwait, E. M. PY - 2010 DA - 2010// TI - Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts JO - J Biol Chem VL - 285 UR - https://doi.org/10.1074/jbc.M110.111732 DO - 10.1074/jbc.M110.111732 ID - Liu2010 ER - TY - JOUR AU - Massagué, J. AU - Chen, Y. -. G. PY - 2000 DA - 2000// TI - Controlling TGF-β signaling JO - Genes Dev VL - 14 ID - Massagué2000 ER - TY - JOUR AU - Mu, Y. AU - Gudey, S. AU - Landström, M. PY - 2012 DA - 2012// TI - Non-Smad signaling pathways JO - Cell Tissue Res VL - 347 UR - https://doi.org/10.1007/s00441-011-1201-y DO - 10.1007/s00441-011-1201-y ID - Mu2012 ER - TY - JOUR AU - Ginnan, R. AU - Jourd'heuil, F. L. AU - Guikema, B. AU - Simons, M. AU - Singer, H. A. AU - Jourd'heuil, D. PY - 2013 DA - 2013// TI - NADPH oxidase 4 is required for interleukin-1beta-mediated activation of protein kinase Cdelta and downstream activation of c-jun N-terminal kinase signaling in smooth muscle JO - Free Radic Biol Med VL - 54 UR - https://doi.org/10.1016/j.freeradbiomed.2012.09.026 DO - 10.1016/j.freeradbiomed.2012.09.026 ID - Ginnan2013 ER - TY - JOUR AU - Shi, L. AU - Chang, Y. AU - Yang, Y. AU - Zhang, Y. AU - Yu, F. S. AU - Wu, X. PY - 2012 DA - 2012// TI - Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0032128 DO - 10.1371/journal.pone.0032128 ID - Shi2012 ER - TY - JOUR AU - Reich, N. AU - Tomcik, M. AU - Zerr, P. AU - Lang, V. AU - Dees, C. AU - Avouac, J. AU - Palumbo, K. AU - Horn, A. AU - Akhmetshina, A. AU - Beyer, C. AU - Xie, W. AU - Bennett, B. L. AU - Distler, O. AU - Schett, G. AU - Distler, J. H. PY - 2012 DA - 2012// TI - Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis JO - Ann Rheum Dis VL - 71 UR - https://doi.org/10.1136/annrheumdis-2011-200412 DO - 10.1136/annrheumdis-2011-200412 ID - Reich2012 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2407/14/640/prepub UR - http://www.biomedcentral.com/1471-2407/14/640/prepub ID - ref35 ER -