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Figure 4 | BMC Cancer

Figure 4

From: GPC3 reduces cell proliferation in renal carcinoma cell lines

Figure 4

Effect of GPC3 on cell proliferation. Cell viability of ACHN and 786-O cells was measured 24 h, 48 h, 72 h, 96 h and 120 h post-transfection with pcDNA3.1 (empty vector) and pcDNA3.1/GPC3 by MTT assay. Data are presented as the mean of two independent experiments ± SEM. Group comparisons were carried out using Student’s t test. A) ACHN cells overexpressing GPC3 experienced a significant reduction in proliferation rate after 48 h (**p < 0.01), 72, 96 and 120 h (***p < 0.0001). B) 786-O overexpressing GPC3 experienced a significant reduction in proliferation rate after 48 h, 72 h, 96 h and 120 h (*** p <0.0001).

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