Figure 7

High MIF expression in metastatic melanoma lesions is associated with worse outcomes. Kaplan-Meier survival curves generated on the basis of quartiles of MIF tumour expression levels in (A) primary and (B) metastatic melanoma tissues correlated against disease-specific survival (GSE8401 dataset). (C) Kaplan-Meier survival curves generated for low and high expressing samples of metastatic melanoma tissues using a 50% cutoff level (GSE8401 dataset). (D) Analysis conducted as per (C) on an independent dataset of metastatic melanoma tissues (GSE19234, n = 38 cases).