Table 4 Grade 3–4 acute and late stage toxicities
Characteristic | Surgery-based group | RT-based group | P-value |
|---|---|---|---|
Total no. patients | 148 | 290 | |
Grade 3–4 acute toxicity | |||
Neutropenia | 50 (33.8%) | 91 (31.4%) | 0.610 |
Anemia | 12 (8.11%) | 41 (14.1%) | 0.067 |
Gastrointestinal reactions | 15 (10.1%) | 13 (4.48%) | 0.036 |
Small bowel obstruction | 3 (2.03%) | 0 (0.00%) | |
Diarrhea | 12 (8.11%) | 13 (4.48%) | |
Grade 3–4 late stage toxicity | |||
Chronic radiation intestinal injury | 11 (7.43%) | 12 (4.14%) | 0.144 |
Small bowel obstruction | 2 (1.35%) | 0 (0.00%) | |
Proctosigmoiditis | 9 (6.08%) | 12 (4.14%) | |
Chronic radiation cystitis | 6 (4.05%) | 7 (2.41%) | 0.378 |
Lower limb lymphedema | 10 (6.76%) | 6 (2.07%) | 0.017 |