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Table 4 Grade 3–4 acute and late stage toxicities

From: Radical hysterectomy with adjuvant radiotherapy versus radical radiotherapy for FIGO stage IIB cervical cancer

Characteristic Surgery-based group RT-based group P-value
Total no. patients 148 290  
Grade 3–4 acute toxicity    
 Neutropenia 50 (33.8%) 91 (31.4%) 0.610
 Anemia 12 (8.11%) 41 (14.1%) 0.067
 Gastrointestinal reactions 15 (10.1%) 13 (4.48%) 0.036
  Small bowel obstruction 3 (2.03%) 0 (0.00%)  
  Diarrhea 12 (8.11%) 13 (4.48%)  
Grade 3–4 late stage toxicity    
 Chronic radiation intestinal injury 11 (7.43%) 12 (4.14%) 0.144
 Small bowel obstruction 2 (1.35%) 0 (0.00%)  
 Proctosigmoiditis 9 (6.08%) 12 (4.14%)  
Chronic radiation cystitis 6 (4.05%) 7 (2.41%) 0.378
Lower limb lymphedema 10 (6.76%) 6 (2.07%) 0.017