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Table 1 Overview of IHC staining results in 26 urothelial cancers

From: Canonical Notch signalling is inactive in urothelial carcinoma

Case # Stage Grade Metastasis NOTCH1 DLL1 JAG1
1 pTa Low - 1 3 2
2 pTa Low - 0 2 2
3 pTa Low - 1 2 2
4 pTa Low - 0 2 1
6 pTa Low - 1 1 1
7 pTa High - 1 2 2
9 pTa High - 1 2 1
12 pTa High - 1 2 2
19 pTa High - 0 1 2
20 pTa High - 0 1 1
25 pTa Low - 1 3 2
8 CIS High - 1 2 2
10 pT1 High - 1 2 2
11 pT1 High - 1 2 2
18 pT1 High - 0 1 1
23 pT1 High - 0 1 1
24 pT1 High - 0 1 1
13 pT2 High - 0 1 1
22 pT2 High - 0 1 1
29 pT2 High - 0 1 1
14 pT3 High + 0 1 1
15 pT3 High - 1 2 2
26 pT3 High + 0 0 0
27 pT4 High + 0 0 1
34 pT4 High + 0 1 1
35 pT4 High + 1 2 1
  1. Intensity of staining was rated by two independent observers as 3 (strong compared to normal bladder urothelium), 2 (comparable to normal), 1 (weak or very weak compared to normal), 0 (undetectable).