Skip to main content
Figure 5 | BMC Cancer

Figure 5

From: Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression

Figure 5

SHARP-2 immunoreactivity. Immunoreactivity of SHARP-2 within the nucleus (open circles) and cytoplasm (closed triangles) of cells from normal breast (Normal), primary cancer (Primary) and LN metastasis tissues is depicted in A. Immunoreactivity was evaluated semiquantitatively using the Q score (intensity x percentage class, score: 0 – 18) method. Intensity of reactivity (score: 0 = negative; 1 = weak; 2 = moderate, and; 3 = strong). Percentage class (score: 1 = 0-4%; 2 = 5-19%; 3 = 20-39%; 4 = 40-59%; 5 = 60-79%; 6 = 80-100%). Data are displayed using the mean ± 2 standard error (SE). Asterisks (**) indicate statistically significant differences at p < 0.01. Representative images demonstrating the distribution of SHARP-2 in the cancer cells of primary cancer tissue samples is depicted in B (i-iv). The scale bar for A, Bii and Biv is 30 μm and for Bi and Biii is 200 μm.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us