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Figure 1 | BMC Cancer

Figure 1

From: Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression

Figure 1

Stromal immunoreactivity of VN, α v integrin and IGFBP-5. Immunoreactivity of VN (A), αv integrin (B) and IGFBP-5 (C) within the stroma surrounding normal breast (Normal), primary cancer (Primary) and LN metastasis tissues is depicted. Immunoreactivity was evaluated semiquantitatively using the Q score (intensity x percentage class, score: 0 – 18) method. Intensity of reactivity (score: 0 = negative; 1 = weak; 2 = moderate, and; 3 = strong). Percentage class (score: 1 = 0-4%; 2 = 5-19%; 3 = 20-39%; 4 = 40-59%; 5 = 60-79%; 6 = 80-100%). Data are displayed using the mean ± 2 standard error (SE). Asterisks (** and ***) indicate statistically significant differences at p < 0.01 and <0.001, respectively. Scale bar = 30 μm.

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