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Table 1 Patient characteristics and their previous therapies at enrollment (n = 9)

From: A study of docetaxel and irinotecan in children and young adults with recurrent or refractory Ewing sarcoma family of tumors

UPN

Primary sites

Metastatic sites at initial diagnosis

Involved sites at enrollment

No. of prior chemotherapy regimens

Prior surgery

Prior radiation therapy

HDC/ASCT

1

Lt ilium

Lungs, pleura, LS spines, Rt femur, and tibia

Lungs, pleura

6

Resection of pelvic mass (NM) and lung nodules (NM)

Yes

Yes

2

Anterior mediastinum and chest wall

Lungs

Lungs, pleura

4

Resection of mediastinal and chest wall mass (PM), and lung nodules (NM)

Yes

Yes

3

Pubis and pelvic cavity

None

PS, lungs, LS spines with epidural sac

4

Resection of pelvic mass (PM)

Yes

No

4

Pubis, Lt ischium, and pelvic cavity

None

PS

5

No

No

No

5

Lt chest wall and ribs

Lungs, pleura

PS, lungs, pleura, brain, liver, kidney

6

Resection of chest wall mass (PM)

Yes

No

6

Abdomino-pelvic cavity

Lungs

Lungs, pleura, and Lt. interlobar L/Ns

3

Resection of abdomino-pelvic mass (PM)

Yes

Yes

7

Lt paraspinal muscle at LS level

Lungs, Lt common iliac L/Ns

PS, lungs, L spines, Lt ilium, and Lt common iliac L/Ns

3

Resection of paraspinal mass (PM) and lung nodules (NM)

Yes

No

8

LS spines with epidural sac and presacral space

None

PS, lungs

3

No

Yes

Yes

9

Lt Humerus

None

Lungs, pleura

3

Resection of humeral mass (NM)

Yes

Yes

  1. ASCT, autologous stem cell transplantation; HDC, high-dose chemotherapy; L, lumbar; L/Ns, lymph nodes; LS, lumbosacral; Lt, left; NM, negative margin; PM, positive margin; PS, primary site; Rt, right; UPN, unique patient number.