Table 4 Acute toxicity (including the preoperative period)
Toxicity | All grades | Grade 1 | Grade 2 | Grade 3 |
|---|---|---|---|---|
GI | Â | Â | Â | Â |
Diarrhea | 11 | 5 | 4 | 2 |
Nausea | 11 | 6 | 5 | 0 |
Appetite loss | 4 | 3 | 1 | 0 |
Bloating | 8 | 3 | 5 | 0 |
Reflux | 3 | 2 | 1 | 0 |
Constipation | 3 | 1 | 2 | 0 |
Hematological | Â | Â | Â | Â |
Anemia | 18 | 12 | 5 | 1 |
Leucopenia | 9 | 5 | 3 | 1 |
Thrombopenia | 8 | 8 | 0 | 0 |
Skin | Â | Â | Â | Â |
Erythema | 10 | 10 | 0 | 0 |
GU | Â | Â | Â | Â |
Frequency/urgency | 3 | 1 | 2 | 0 |
Dysuria | 4 | 3 | 1 | 0 |
Bladder obstruction | 1 | 0 | 1 | 0 |
Ureter obstruction | 1 | 0 | 0 | 1 |
Infection | 2 | 0 | 1 | 1 |
Other | Â | Â | Â | Â |
Pain | 6 | 6 | 0 | 0 |
Fatigue | 2 | 1 | 1 | 0 |
Motor neuropathy* | 1 | 0 | 1 | 0 |
Varicocele | 1 | 0 | 1 | 0 |
Hypokalemia | 1 | 1 | 1 | 1 |