Figure 1

Inhibition of miR-1246 reduced migration and invasion of SMMC7721 and BEL7402. (A, B) Transwell migration (n = 4) and invasion (n = 4) assays showed that SMMC7721 cells transfected with the miR-1246 inhibitor (800 nM) had lower invasive and migratory potentials than the control (inhibitor control). (A) is a microscopic image of crystal violet staining; (B) shows the statistical results. (C, D) Transwell migration (n = 4) and invasion (n = 4) assays showed that BEL7402 cells transfected with the miR-1246 inhibitor (800 nM) had lower invasive and migratory potentials than the control (inhibitor control). (C) is a microscopic image of crystal violet staining; (D) shows the statistical results. Data represent the mean ± SD of four independent experiments. *P < 0.01.