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Table 1 Acute radiation mouse flank skin reaction scoring criteria

From: Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model

Score

Observation

0.00

Normal

0.25

50/50 doubtful if there is any difference from normal

0.50

Very slight reddening

0.75

Definite but slight reddening

1.00

Severe reddening

1.25

Severe reddening with white scale, “papery” aspect of the skin

1.50

Moist breakdown in one very small area with scaly or crusty appearance

1.75

Moist desquamation in more than one small area

2.00

Moist desquamation of larger area: 10% of the irradiated area

2.25

Moist desquamation of larger area: 33% of the irradiated area

2.50

Moist desquamation of larger area: 50% of the irradiated area

2.75

Moist desquamation of larger area: 66% of the irradiated area

3.00

Moist desquamation of most of the irradiated area with possible slight moist exudates

3.25

Moist desquamation of most of the irradiated area with definite moist exudates

3.50

Moist desquamation of the irradiated area with moist exudates, necrosis

  1. Adapted from Douglas & Fowler, 1976; Douglas & Fowler, 2012.