Figure 2
From: MiR-181b sensitizes glioma cells to teniposide by targeting MDM2
MiR-181b level is positively related to glioma cell sensitivity to teniposide. A: Cells expressing low levels of miR-181b had high IC50, while cells with high miR-181b had low IC50 (r = -0.691, p < 0.01). B: MiR-181b was successfully overexpressed in U87 cells compared with vector control (*p < 0.01). C: The IC50 of miR-181b overexpressed U87 cells was significantly lower than control cells (1.3 ± 0.34 μg/ml versus 6.2 ± 0.87 μg/ml).