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Table 2 IC 50 values for Cisplatin in isogenic ovarian cancer cell line pairs

From: Bithionol inhibits ovarian cancer cell growth In Vitro- studies on mechanism(s) of action

   48 hrs 72 hrs
1 IGROV-1 13 ± 1 3 ± 0.05
2 IGROV-1 CDDP 60 ± 8 18 ± 1
3 A2780 22 ± 3 10 ± 2
4 A2780-CDDP 42 ± 6 23 ± 4
  1. IC50 values (μM) for Cisplatin - Mean ± SD.
  2. IC50 values for Cisplatin in isogenic ovarian cancer cell line pairs consisting of Cisplatin-sensitive parental lines and stable Cisplatin-resistant sub-lines derived by in vitro selection with Cisplatin.