Figure 2
From: MMP-9 expression varies according to molecular subtypes of breast cancer
Expression of MMP-9 mRNA in human breast cancer cell lines. In silico analysis showing elevated MMP-9 mRNA expression levels in basal-like breast cancer cell lines (e.g. CAL85-1, HCC1395, HCC1143, DU4475, HCC1937, MDA-MB-231 and HCC38). Luminal breast cancer cell lines with HER2 amplification also display stronger MMP-9 mRNA expression (AU565, UAA-893 and HCC2218). MCF7 and KPL1 cell lines are the only luminal cell lines with mildly elevated MMP-9 mRNA expression. (B = basal, L = luminal, L + H = Luminal with HER2 amplification).