IHC score | Good responders | Poor responders | p-value | |
---|---|---|---|---|
Phosphorylated STAT3 | 0 or 1 | 16 | 9 | 0.036 |
2 or 3 | 6 | 14 | ||
VPP(PR) = 14/20 = 70%/VPN(GR) = 16/25 = 64% | ||||
Phosphorylated ERK1 | 0 or 1 | 17 | 8 | 0.007 |
2 or 3 | 5 | 15 | ||
VPP(PR) = 15/20 = 75%/VPN(GR) = 17/25 = 68% | ||||
Phosphorylated STAT3 and ERK1 | Both 0-1 | 12 | 4 | 0.003 |
Intermediate | 8 | 7 | ||
Both 2-3 | 1 | 10 | ||
VPP(both/PR) = 10/11 = 91%/VPN(both/GR) = 12/16 = 75% |