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Figure 3 | BMC Cancer

Figure 3

From: High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients

Figure 3

Expression of LSD1, HDAC2 and SIRT1 in different tumor stages. We included 182 patients with a stage I disease, 227 patients with a stage II disease and 51 patients with a stage III tumor. (A) Boxplot showing the percentage of positive tumor cells for LSD1 versus the TNM tumor stage (I-III) at moment of diagnosis. (B) HDAC2 expression levels versus TNM tumor stage shown in a boxplot. (C) The expression levels of SIRT1 versus TNM tumor stage represented in a boxplot. The thick horizontal lines represent the mean percentage of positive tumor cells in each category. Outliers are represented by circles. The p-values were calculated using the one-way ANOVA method and p-values ≤0.05 are considered as significant.

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BMC Cancer

ISSN: 1471-2407

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