Figure 4From: PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitrohepatocellular carcinoma models Excision/synthesis abilities of liver cancer cells. (A) Total excision/synthesis abilities were analyzed using damaged plasmids microarray containing six DNA damage types and by adding total fluorescence intensity of all DNA lesions. (B) Excision/synthesis abilities for each type of DNA lesion (cyclobutane pyrimidine dimers and 6–4 photoproducts (CPD-64), T-T inter- and intra-strand crosslinks psoralen adducts (Pso), 8-oxoguanine (8oxoG), alkylated bases (AlkB), abasic sites (AbaS) and cytosine and thymine glycols (glycol).Back to article page