Table 2 Associations between B7-H3 expression and clinicopathological parameters – total study cohort
Parameter | Â | Patients number (%) | Cytoplasmic/membrane B7-H3 | Nuclear B7-H3 | Total1B7-H3 | Stromal B7-H3 |
|---|---|---|---|---|---|---|
Gender | Male | 342 (47) | 298 (87) | 92 (27) | 303 (89) | 269 (79) |
| Â | Female | 389 (53) | 329 (85) | 105 (27) | 334 (86) | 291 (75) |
| Â | p-value | Â | 0.34 | 1.0 | 0.32 | 0.26 |
TNM | I | 103 (14) | 88 (85) | 33 (32) | 89 (86) | 79 (77) |
| Â | II | 307 (42) | 268 (87) | 78 (25) | 272 (89) | 250 (81) |
| Â | III | 186 (25) | 161 (87) | 58 (31) | 165 (89) | 137 (74) |
| Â | IV | 135 (18) | 110 (81) | 28 (21) | 111 (82) | 94 (70) |
| Â | p-value | Â | 0.29 | 0.22 | 0.27 | 0.03 |
pT | 1 | 27 (4) | 20 (74) | 9 (33) | 22 (81) | 20 (74) |
| Â | 2 | 98 (13) | 86 (88) | 32 (33) | 86 (88) | 73 (74) |
| Â | 3 | 534 (73) | 463 (87) | 135 (25) | 471 (88) | 419 (78) |
| Â | 4 | 72 (10) | 58 (81) | 21 (29) | 58 (81) | 48 (67) |
| Â | p-value | Â | 0.93 | 0.34 | 0.72 | 0.62 |
pN | 0 | 455 (63) | 393 (86) | 119 (26) | 398 (87) | 363 (80) |
| Â | 1 | 197 (27) | 169 (86) | 61 (31) | 173 (88) | 147 (75) |
| Â | 2 | 74 (10) | 62 (84) | 16 (22) | 63 (85) | 49 (66) |
| Â | p-value | Â | 0.58 | 1.0 | 0.74 | 0.007 |
Differentiation | Well | 72 (10) | 62 (86) | 25 (35) | 63 (88) | 54 (75) |
| Â | Intermediate | 549 (78) | 469 (85) | 144 (26) | 477 (87) | 423 (77) |
| Â | Poor | 87 (12) | 74 (85) | 22 (25) | 75 (86) | 67 (77) |
| Â | p-value | Â | 0.91 | 0.21 | 0.82 | 0.85 |
Tumour localisation 2 | Colon | 546 (75) | 473 (87) | 150 (27) | 481 (88) | 417 (76) |
| Â | Rectum | 180 (25) | 150 (83) | 46 (26) | 152 (84) | 141 (78) |
| Â | p-value | Â | 0.34 | 0.7 | 0.2 | 0.61 |