Table 3 Clinical and tumor characteristics of the whole patient cohort before TACE treatment according to tumor response
From: TACE performed in patients with a single nodule of Hepatocellular Carcinoma
Variable | CR (n = 95) | Non-CR (n = 50) | P |
|---|---|---|---|
Gender male, n (%) | 0.122 | ||
Male | 71 (70) | 31 (30) | |
Female | 24 (56) | 19 (44) | |
Age, median (years) (range) | 63 (36–83) | 67.5 (45–84) | 0.099 |
Cause of disease, n (%) | 0.928 | ||
HBV | 7 (50) | 7 (50) | |
HCV | 54 (66) | 28 (34) | |
Alcohol | 15 (79) | 4 (21) | |
Multiple etiologies | 9 (53) | 8 (47) | |
Unknown | 9 (75) | 8 (25) | |
Other | 1 (100) | 3 (0) | |
Lesion location, n (%) | 0.453 | ||
Right lobe | 72 (67) | 35 (33) | |
Left lobe | 23 (61) | 15 (39) | |
TACE selectivity, n (%) | 0.992 | ||
Lobar | 5 (50) | 5 (50) | |
Selective | 45 (63) | 26 (37) | |
Superselective | 45 (70) | 19 (30) | |
Tumor size, n (cm) (%) | 0.017 | ||
≤3.0 | 65 (73) | 24 (27) | |
>3.0 | 30 (54) | 26 (46) | |
Milan criteria, n (%) | 0.004 | ||
Within (≤5.0 cm) | 92 (69) | 41 (31) | |
Beyond (>5.0 cm) | 3 (25) | 9 (75) | |
Portal vein thrombosis, n (%) | 0.789 | ||
Absent | 83 (65) | 45 (35) | |
Bland thrombosis | 12 (71) | 5 (29) | |
Serum AFP, median (ng/mL) (range) | 13.0 (1.0 – 10000.0) | 21.0 (2.0 – 39576.0) | 0.094 |
Ascites, n (%) | 1.000 | ||
Absent | 77 (66) | 40 (34) | |
Present | 18 (64) | 10 (36) | |
Encephalopathy, n (%) | 1.000 | ||
Absent | 93 (66) | 49 (34) | |
Slight | 2 (67) | 1 (33) | |
Serum total bilirubin, median (mg/dL) (range) | 1.39 (0.30 – 7.56) | 1.24 (0.35 – 7.72) | 0.594 |
Serum albumin, median (g/dL) (range) | 3.60 (2.10 – 5.00) | 3.75 (2.40 – 4.90) | 0.064 |
Serum INR, median (range) | 1.29 (1.00 – 1.83) | 1.23 (1.00 – 1.97) | 0.365 |
Hepatic function, n (%) | 0.155 | ||
CPT-A | 55 (61) | 35 (39) | |
CPT-B | 40 (73) | 15 (27) | |
Performance status, n (%) | 0.775 | ||
0 | 86 (66) | 44 (34) | |
1 | 9 (60) | 6 (40) | |
BCLC stage, n (%) | 0.077 | ||
0 – A | 83 (70) | 35 (30) | |
B | 3 (25) | 9 (75) | |
C | 9 (60) | 6 (40) | |
MELD score, median (range) | 12 (7 – 19) | 11 (6 – 24) | 0.637 |