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Figure 2 | BMC Cancer

Figure 2

From: Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke

Figure 2

Detection of genotoxicity through in vitro erythropoiesis. A Representative micrograph of Day 2 harvested cultures at 100x magnification. The arrows indicate normally enucleated PCEs, and the arrowhead indicates a micronucleated PCE. Scale bar = 8 μM. B Nf1 −/− Lin- BM cultures exhibit sensitivity to MN formation after in vitro exposure to HQ. The response of this erythropoietic culture system to HQ treatment is quantified by MN frequency in PCEs. Data presented is the mean of the “n” independent cultures ± SD.

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BMC Cancer

ISSN: 1471-2407

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