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Figure 5 | BMC Cancer

Figure 5

From: Fluoxetine modulates breast cancer metastasis to the brain in a murine model

Figure 5

Fluoxetine does not increase brain-resident tumor growth. Nu/Nu mice treated with fluoxetine were injected with CNS-1 cells into the frontal cortex, as described. A) A representative image of a tumor formed after intracranial injection of CNS-1 cells. Scale bar: 200 μm. Three separate measures were used to quantify tumor growth. None of them showed significant effects of fluoxetine administration: number of sections containing CNS-1 tumors, p = 0.76 (B); total pixel count analysis of brain sections with CNS-1 tumors, p = 0.68 (C); tumor width, as determined by the average of four largest values from each animal, p = 0.86 (D). n = 9-10 per group. Scale bar, 100 μm.

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