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Table 2 Joint effects of vaccination with BCG and/or vaccinia with history of serious infectious disease on melanoma risk a

From: The biography of the immune system and the control of cancer: from St Peregrine to contemporary vaccination strategies

Co-variable serious infectious disease Vaccination with BCG and vaccinia Concomitant effect (type of)
  Yes No  
≥1 1.00 n = 96 1.21 ((0.67-2.06) n = 12  
0 1.12 (0.30-4.30) n = 516 3.03 (1.58-5.97) n = 88 Cumulative
  Vaccination with BCG or vaccinia  
Serious infectious disease    
  Yes No  
≥1 1.00 n = 98 1.97 (1.14-3.56) n = 12  
0 1.28 (0.35-4.90) n = 420 3.45 (1.79-6.80) n = 89 Cumulative
  1. aData expressed as Odds Ratios (95% Confidence intervals), adjusted for centre, sex, age, ethnic origin, skin type, freckling index, number of naevi and number of sunburns. n = number of cases and controls. Summarized from the FEBIM study [82, 83].