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Figure 2 | BMC Cancer

Figure 2

From: The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein

Figure 2

mRNA expression of hypoxia-related genes under normoxia versus hypoxia in MDA-MB-231 cells. Normalised Ct values for HIF-1α (left) and angiopoetin-like 4 (right), as analysed by the Human Hypoxia Signalling Pathway PCR array. Boxplots present the normalised Ct values for MDA-MB-231 wt, EV and dnHIF cells exposed to normoxic (N) or hypoxic (H) conditions for 24 h. A higher Ct value corresponds to lower mRNA expression in the biological sample.

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