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Table 3 Percentage ER hypermethylation in relation to tumor phenotype

From: ESR1gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients

Test result Luminal A Luminal B Triple negative HER2(+) P
n % n % n % n %
(−) ESR1 < 0.02 28 (71%) 14 (64%) 3 (20%) 4 (40%) <0.05
(+) ERS1 > 0.02 11 (28%) 8 (36%) 12 (80%) 6 (60%) <0.05