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Figure 4 | BMC Cancer

Figure 4

From: Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma

Figure 4

The role of MIC-1 in evaluating therapy response and surveillance of PDAC after curative resection. a. Comparison of serum MIC-1 levels from all PDAC patients before surgery (Pre) and one month after postsurgical removal of primary tumors (Post). (n = 133). b. Comparison of serum MIC-1 levels in 102 PDAC patients who underwent potentially curative surgeries. c. Comparison of serum MIC-1 levels in 31 PDAC patients who underwent noncurative surgeries. d. In 35 patients with documented recurrence, the serum MIC-1 levels were increased again to the preoperative levels. e. Comparison of serum MIC-1 levels between the baseline MIC-1 levels before the first operation and that at time of tumor recurrence in 35 patients with recurrence. f. A significant correlation (r = 0.965; P < 0.001) was found between MIC-1 levels before the first operation and after recurrence.

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